Selenium in human Health and Disease
Selenium is an essential micronutrient found in Brazil nuts, chicken, fish, turkey, crab, nuts, cereal and eggs. Selenium is an “essential nutrient”, meaning our bodies cannot make it, and so we have to get it from our diet. Without it the heart, joints, eyes, immune system and reproductive system can suffer. We require 55 micrograms of selenium to maintain proper health and this selenium we must obtain through dietary sources.
What is Selenium
Selenium is a non-metal element that occurs in the earth’s crust. Selenium is necessary in the body’s production of selenoproteins. There are around 25 selenoproteins in humans and many of these are enzymes that act to protect the body against oxidative damage. Since the ageing process, as well as certain diseases, including cancer and cardiovascular disease, is associated with an increase in oxidative damage, maintaining adequate selenium intakes may provide some protection against these processes.
Where is Selenium found
Plants pick up selenium from soil. The selenium content in plant foods depends on the concentration of selenium in the soil where the plants grow. Seafood and organ meats are rich in selenium. Other foods that have selenium include muscle meats, grains and dairy products. It can also be found in drinking water in some places.
People living in places where the soil is selenium deficient have low selenium levels. People who smoke cigarettes or drink alcohol often are more likely to have selenium deficiency. Crohn’s disease, ulcerative colitis, or other conditions that interfere with how the body absorbs selenium can lead to low selenium levels. Kidney dialysis patients may also become low in selenium. The chemotherapy drug cisplatin can lower selenium levels in the blood, but it is not known if cisplatin can lead to a significant deficiencies.
- Excessive Hair loss
- Discoloration of the Nails and Skin
- Fatigue and Tiredness
- Repeated miscarriages
- Low immunity
Selenium deficiency leads to…..
Selenium deficiency can impair immune function, increase incidence of cancer, cardiovascular and other degenerative diseases as well as overall mortality. In humans, selenium deficiency can result in Keshan disease, a juvenile cardiomyopathy apparent in the Keshan region in China. In China especially, low selenium intakes have also been reported to be associated with high incidence of hepatitis B virus infections.
Why people take Selenium supplement:
- Selenium has attracted attention because of its antioxidant properties
- Selenium supplements in particular are helpful for people with asthma, and reduce the risk of rheumatoid arthritis and cardiovascular disease
- Selenium can slow the aging process, cognitive decline and dementia
- Selenium can slow down the progression of HIV
- Selenium can reduce the risk of lung, prostate and colorectal cancers
- Selenium acts as a powerful protector of the thyroid and regulates the production of reactive oxygen within the gland
- Selenium can boost fertility. It is required for proper sperm motility and also increases blood flow
- Dandruff shampoos use selenium sulfide as a topical treatment
Do not consume selenium too much
The human body can tolerate quite high levels of selenium without adverse effects on health. However, at high doses, more than 900 mg selenium/day, selenium can elicit toxic effects collectively termed selenosis, with symptoms including gastrointestinal upset, hair loss, nausea, irritability, fatigue and mild nerve damage.
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