Stress, depression and anxiety which roots from brain can directly influence the overall health of the skin. The fact that stress can damage skin in many a ways and trigger acne and psoriasis is known to many. But it would be of interest to learn that the relationship between brain and skin is two way. Not only does the hormones triggered by brain affect the skin, but the appearance of our skin which at times can cause shame, poor self-image, and low self-esteem can significantly impact our mental health and emotional well-being. The relation between brain and skin is not just about stress alone, but this relationship starts from embryonic stage. The fact is both skin cells and brain cells develop from the same kind of embryonic tissue, called ectoderm.